"The operating system is not presently configured to run this application"

/Problem solved, fix under problem description./

Hi. My Word and PowerPoint work just fine, but Excel doesnt. I tried fast fix, long fix, changing registry, sfc, dism, healthrestore, reinstalling Office (newer version now), trying on the new user profile and other things. The problem is "The operating system is not presently configured to run this application". Did anyone meet this problem? I urgently need to use Excel later today ;( maybe someone had same problem and fixed it? Version 2021 LTSC.

Solution / Fix (if helps, give upvote): The problem was that the default installation disc was changed from C to D. Changing it back to C in the settings wasn't enough. I had to change it also in regedit in HKEY_LOCAL_MACHINE\SOFTWARE\Microsoft\Windows\CurrentVersion and there I changed the ProgramFilesDir and ProgramFilesDir (x86) to disc C. Unfortunately, despite the changes in the settings, the registry didn't change on its own so I had to do it manually. Then I had to run a long online repair of Office (go to *add or remove programs - Office - modify, long repair). After the first run, an error occurred, but Safe Mode started. I shut down Excel, turned it back on, and it worked. If you are here, you probably have similar problem. I hope it will work for you!*